LH21

LH-21 is a potent in vivo neutral cannabinoid CB1 receptor antagonist. LH-21 reduces food intake and body weight gain in obese Zucker rats. , and displays efficacy as a feeding inhibitor[1].

Product Specifications

CAS Number

[611207-11-5]

UNSPSC

12352005

Hazard Statement

H301

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/lh21.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCC1=NN(C(C2=CC=C(C=C2)Cl)=N1)C3=CC=C(C=C3Cl)Cl

Molecular Formula

C20H20Cl3N3

Molecular Weight

408.75

Precautions

H301

References & Citations

[1]Francisco Javier Pavon, et al. Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5- (4-chlorophenyl) -1- (2,4-dichlorophenyl) -3-hexyl-1H-1,2,4-triazole--LH 21. Neuropharmacology