LH21
LH-21 is a potent in vivo neutral cannabinoid CB1 receptor antagonist. LH-21 reduces food intake and body weight gain in obese Zucker rats. , and displays efficacy as a feeding inhibitor[1].
Product Specifications
CAS Number
[611207-11-5]
UNSPSC
12352005
Hazard Statement
H301
Target
Cannabinoid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/lh21.html
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCC1=NN(C(C2=CC=C(C=C2)Cl)=N1)C3=CC=C(C=C3Cl)Cl
Molecular Formula
C20H20Cl3N3
Molecular Weight
408.75
Precautions
H301
References & Citations
[1]Francisco Javier Pavon, et al. Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5- (4-chlorophenyl) -1- (2,4-dichlorophenyl) -3-hexyl-1H-1,2,4-triazole--LH 21. Neuropharmacology
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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