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IL-4-inhibitor-1

IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 μM[1].

Product Specifications

CAS Number

[1332184-63-0]

UNSPSC

12352005

Target

Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/il-4-inhibitor-1.html

Purity

98.04

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N#CC1=C(C2=CC=C(O)C(O)=C2)C=C(C3=CC=C(F)C=C3)N=C1N

Molecular Formula

C18H12FN3O2

Molecular Weight

321.31

References & Citations

[1]Sean P Quinnell, et al. A Small-Molecule Inhibitor to the Cytokine Interleukin-4. ACS Chem Biol. 2020 Oct 16;15 (10) :2649-2654.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

IL-4

Available Sizes

Curated Selection

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