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Iprobenfos

Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos can phosphorylate the -OH group on the serine residue in the active (esteratic) site of ChEs and so inhibit both AChE and BChE activity[1][2].

Product Specifications

CAS Number

[26087-47-8]

UNSPSC

12352005

Hazard Statement

H302, H411

Target

Cholinesterase (ChE) ; Fungal

Type

Reference compound

Related Pathways

Anti-infection; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/iprobenfos.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=P(OC(C)C)(SCC1=CC=CC=C1)OC(C)C

Molecular Formula

C13H21O3PS

Molecular Weight

288.34

Precautions

H302, H411

References & Citations

[1]Jee-Hyun Jung, et al. Characterization of Cholinesterases in Marbled Sole, Limanda Yokohamae, and Their Inhibition in Vitro by the Fungicide Iprobenfos. Mar Environ Res. 2007 Jun;63 (5) :471-8.|[2]Zuo-Qian Wang, et al. A Putative Zn 2 Cys 6 Transcription Factor Is Associated With Isoprothiolane Resistance in Magnaporthe oryzae. Front Microbiol. 2018 Oct 31;9:2608.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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