Bintrafusp alfa
Product Specifications
UNSPSC Description
Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer[1].
Target Antigen
TGF-β Receptor
Type
Inhibitory Antibodies
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bintrafusp-alfa.html
Purity
97.96
Solubility
H2O
Smiles
[Bintrafusp alfa]
References & Citations
[1]Strauss J, et, al. Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with human papillomavirus-associated malignancies. J Immunother Cancer. 2020 Dec;8(2):e001395.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P99480/Bintrafusp-alfa-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99480/Bintrafusp-alfa-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
1918149-01-5
Available Sizes
Curated Selection
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