SPARC Recombinant Rabbit Monoclonal Antibody [PSH06-23]
Osteonectin (ON) also known as secreted protein acidic and rich in cysteine (SPARC) or basement-membrane protein 40 (BM-40) is a protein that in humans is encoded by the SPARC gene. Osteonectin is a glycoprotein in the bone that binds calcium. It is secreted by osteoblasts during bone formation, initiating mineralization and promoting mineral crystal formation. Osteonectin also shows affinity for collagen in addition to bone mineral calcium. A correlation between osteonectin over-expression and ampullary cancers and chronic pancreatitis has been found.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
SPARC, ON
Swiss Prot
P09486 Human
Cellular Locus
Secreted, extracellular space, extracellular matrix, basement membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human SPARC aa 1-303.
Isotype
IgG
Clone
PSH06-23
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
A375 cell lysate, SH-SY5Y cell lysate, MG-63 cell lysate, RWPE-1 cell lysate.
Concentration
1 mg/mL
Dilution
WB: :1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 35 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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