L-Canavanine (sulfate)
L-Canavanine sulfate is a selective inhibitor of inducible NO synthase.
Product Specifications
CAS Number
[2219-31-0]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/L-Canavanine_sulfate.html
Concentration
10mM
Purity
99.39
Solubility
H2O : 100 mg/mL (ultrasonic; warming)
Smiles
N[C@@H](CCONC(N)=N)C(O)=O.O=S(O)(O)=O
Molecular Formula
C5H14N4O7S
Molecular Weight
274.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Teale DM, et al. L-canavanine restores blood pressure in a rat model of endotoxic shock. Eur J Pharmacol. 1994 Dec 12;271 (1) :87-92.|[2]Nurcahyanti AD, et al. Cytotoxic potentiation of vinblastine and paclitaxel by L-canavanine in human cervical cancer and hepatocellular carcinoma cells. Phytomedicine. 2015 Dec 15;22 (14) :1232-7.|[3]Green MH, et al. Antitumor activity of L-canavanine against L1210 murine leukemia. Cancer Res. 1980 Mar;40 (3) :535-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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