L-Canavanine (sulfate)

L-Canavanine sulfate is a selective inhibitor of inducible NO synthase.

Product Specifications

CAS Number

[2219-31-0]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/L-Canavanine_sulfate.html

Concentration

10mM

Purity

99.39

Solubility

H2O : 100 mg/mL (ultrasonic; warming)

Smiles

N[C@@H](CCONC(N)=N)C(O)=O.O=S(O)(O)=O

Molecular Formula

C5H14N4O7S

Molecular Weight

274.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Teale DM, et al. L-canavanine restores blood pressure in a rat model of endotoxic shock. Eur J Pharmacol. 1994 Dec 12;271 (1) :87-92.|[2]Nurcahyanti AD, et al. Cytotoxic potentiation of vinblastine and paclitaxel by L-canavanine in human cervical cancer and hepatocellular carcinoma cells. Phytomedicine. 2015 Dec 15;22 (14) :1232-7.|[3]Green MH, et al. Antitumor activity of L-canavanine against L1210 murine leukemia. Cancer Res. 1980 Mar;40 (3) :535-7.