Marstacimab
Marstacimab (PF-06741086) is an anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody. Marstacimab can be used for the research of hemophilia[1][2].
Product Specifications
CAS Number
1985638-39-8
Product Name Alternative
PF-06741086
UNSPSC
12352203
Target
Thrombin; Tissue Factor Pathway Inhibitor (TFPI)
Type
Inhibitory Antibodies
Related Pathways
Cytoskeleton; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/marstacimab.html
Purity
96.27
Solubility
10 mM in DMSO
Smiles
[Marstacimab]
Molecular Weight
(145.98 kDa)
References & Citations
[1]Patel-Hett S, et al. Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas. Haemophilia. 2019 Sep;25 (5) :797-806.|[2]Pittman DD, et al. Hemostatic efficacy of marstacimab alone or in combination with bypassing agents in hemophilia plasmas and a mouse bleeding model. Res Pract Thromb Haemost. 2022 Mar 16;6 (2) :e12679.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Available Sizes
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