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3-Hydroxybutyric acid (sodium)

3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids[1].

Product Specifications

CAS Number

[150-83-4]

Product Name Alternative

β-Hydroxybutyric acid (sodium)

UNSPSC

12352211

Hazard Statement

H302

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/3-hydroxybutyric-acid-sodium.html

Purity

99.82

Solubility

DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(O)CC(O[Na])=O

Molecular Formula

C4H7NaO3

Molecular Weight

126.09

Precautions

H302

References & Citations

[1]Hsu TT, et al. 3-Hydroxybutyric acid interacts with lipid monolayers at concentrations that impair consciousness. Langmuir. 2013 Feb 12;29 (6) :1948-55.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Citation 01

BMC Neurol. 2025 Apr 10;25 (1) :153.|Research Square Preprint. 2024 Aug 08.|Acta Pharm Sin B. 2025 Mar;15 (3) :1430-1446.|Biochem Biophys Res Commun. 2024 Jul 25:734:150449.|Cancer Cell. 2024 Oct 14;42 (10) :1729-1746.e8.|Cell Host Microbe. 2024 Dec 12:S1931-3128 (24) 00444-X.|Cell Metab. 2023 Jan 3;35 (1) :200-211.e9.|Cells. 2022 Sep 25;11 (19) :2987.|Free Radic Biol Med. 2025 Oct 23:241:914-932.|J Nanobiotechnology. 2022 Mar 9;20 (1) :120.|J Nutr Biochem. 2023 Aug:118:109335.|J Pathol. 2025 Oct 23.|Mol Cell. 2023 Sep 7;83 (17) :3171-3187.e7.|Nat Commun. 2025 May 7;16 (1) :4224.|Nat Metab. 2025 Jul;7 (7) :1330-1343.|Nat Protoc. 2024 May;19 (5) :1311-1347.|Pharmaceuticals (Basel) . 2025 Feb 6;18 (2) :219.|Redox Biol. 2024 May 16.|Signal Transduct Target Ther. 2024 Dec 30;9 (1) :367.

Available Sizes

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