5'-Guanylic acid-15N5 (dilithium)
5'-Guanylic acid-15N5 (5'-GMP-15N5 dilithium; 5'-guanosine monophosphate-15N5) dilithium is 15N labeled 5'-Guanylic acid (HY-N5134) . 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
Product Specifications
Product Name Alternative
5'-GMP-15N5 (dilithium) ; 5'-guanosine monophosphate-15N5 (dilithium)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/5-guanylic-acid-15n5-dilithium.html
Concentration
100 mM in 131.56 μL Tris HCl/H2O buffer pH=7.5
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=P(O[Li])(O[Li])OC[C@H]1O[C@@H]([15N]2C([15N]=C([15NH2])[15NH]C3=O)=C3[15N]=C2)[C@H](O)[C@@H]1O
Molecular Formula
C10H12Li2 15N5O8P
Molecular Weight
380.05
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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