Elab Fluor® 488 Anti-Mouse CD45R (B220) Antibody[RA3-6B2]
Product Specifications
Background
CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker. CD19, however, may be more appropriate for B cell specificity.
Abbreviation
CD45R
Gene ID
19264;5788
UniProt
Q64224
Host
Rat
Reactivity
Mouse
Target
CD45R; B220
Clonality
Monoclonal
Clone
RA3-6B2
Conjugation
Elab Fluor®488
Applications
FCM
Concentration
0.5 mg/mL
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Product Datasheet
https://789.bio/ea/5lmepk
Product MSDS
https://789.bio/eb/qiimPR
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Rat IgG2a, κ
Available Sizes
Curated Selection
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