Monoethyl pimelate
Monoethyl pimelate is a PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S, R, S) -AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1].
Product Specifications
CAS Number
[33018-91-6]
UNSPSC
12352211
Hazard Statement
H315, H319
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/monoethyl-pimelate.html
Purity
99.09
Solubility
10 mM in DMSO
Smiles
O=C(OCC)CCCCCC(O)=O
Molecular Formula
C9H16O4
Molecular Weight
188.22
Precautions
H315, H319
References & Citations
[1]Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25 (12) :1938-1947.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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