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Monoethyl pimelate

Monoethyl pimelate is a PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S, R, S) -AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1].

Product Specifications

CAS Number

[33018-91-6]

UNSPSC

12352211

Hazard Statement

H315, H319

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/monoethyl-pimelate.html

Purity

99.09

Solubility

10 mM in DMSO

Smiles

O=C(OCC)CCCCCC(O)=O

Molecular Formula

C9H16O4

Molecular Weight

188.22

Precautions

H315, H319

References & Citations

[1]Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25 (12) :1938-1947.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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