Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Rat CLEC12A / MICL / CLL-1 Protein, His Tag

CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.

Product Specifications

Background

CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 26.0 kDa. The protein migrates as 32-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

B4F798-1

Expression Region

Tyr 65 - Leu 269

Host

HEK293

Target

CLEC12A

Conjugation

Unconjugated

Tag

N-10xHis

Source

Rat

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

26.0 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

1mg*1

Host or Source

HEK293

Species

Rat

Protein ID

B4F798-1

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

4alpha-Phorbol
TBZ2994 unit

4alpha-Phorbol

Ask
View Details
Toll-Like Receptor 7 Rabbit mAb
MBS4762413-01 0.1 mL

Toll-Like Receptor 7 Rabbit mAb

Ask
View Details
Toll-Like Receptor 7 Rabbit mAb
MBS4762413-02 5x 0.1 mL

Toll-Like Receptor 7 Rabbit mAb

Ask
View Details
PCMV-3xFLAG-CCNL2 (human) -Neo
BZ60636 1 Vial

PCMV-3xFLAG-CCNL2 (human) -Neo

Ask
View Details
RNA Polymerase II (MGC75453, B220, DNA-directed RNA Polymerase II Largest Subunit, hRPB220, hsRPB1, POLR2, POLR2A, POLRA, RNA Polymerase II (DNA directed) Polypeptide A 220kD, RPB1, RPB220, RPBh1, RpIILS, RPO2, RPOL2) (MaxLight 750) discontinued
R2039-21-ML750 100 µL

RNA Polymerase II (MGC75453, B220, DNA-directed RNA Polymerase II Largest Subunit, hRPB220, hsRPB1, POLR2, POLR2A, POLRA, RNA Polymerase II (DNA directed) Polypeptide A 220kD, RPB1, RPB220, RPBh1, RpIILS, RPO2, RPOL2) (MaxLight 750) discontinued

Ask
View Details
Xcl1 siRNA Oligos set (Rat)
50508176 3x 5 nmol

Xcl1 siRNA Oligos set (Rat)

Ask
View Details