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WR99210

WR99210 is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC50P. falciparum and P. falciparum strains (including PyrimethamineP. falciparum strains) as well as T. gondii[1][2][3].

Product Specifications

CAS Number

47326-86-3

Product Name Alternative

BRL 6231 (free base)

UNSPSC

12352005

Target

Dihydrofolate reductase (DHFR) ; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/wr99210.html

Purity

99.10

Solubility

DMSO : 5 mg/mL (ultrasonic)

Smiles

CC1(N=C(N=C(N1OCCCOC2=C(C=C(C(Cl)=C2)Cl)Cl)N)N)C

Molecular Formula

C14H18Cl3N5O2

Molecular Weight

394.68

References & Citations

Plasmodium falciparum

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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