WR99210
WR99210 is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC50P. falciparum and P. falciparum strains (including PyrimethamineP. falciparum strains) as well as T. gondii[1][2][3].
Product Specifications
CAS Number
[47326-86-3]
Product Name Alternative
BRL 6231 (free base)
UNSPSC
12352005
Target
Dihydrofolate reductase (DHFR) ; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/wr99210.html
Purity
99.10
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
CC1(N=C(N=C(N1OCCCOC2=C(C=C(C(Cl)=C2)Cl)Cl)N)N)C
Molecular Formula
C14H18Cl3N5O2
Molecular Weight
394.68
References & Citations
Plasmodium falciparum
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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