Coenzyme Q8

Coenzyme Q8 (Ubiquinone 8) is an isoprenoid quinone that mediates electron transfer within the aerobic respiratory chain and reduces oxidative stress. Coenzyme Q8 maintains bacterial respiratory function and enhances host resistance to bacterial infection. Coenzyme Q8 stimulates macrophage phagocytosis and increases antibody-producing cells. Coenzyme Q8 can be used in infectious disease research[1][2].

Product Specifications

CAS Number

[2394-68-5]

Product Name Alternative

Ubiquinone 8

UNSPSC

12352204

Target

Bacterial; Endogenous Metabolite

Type

Enzyme

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/coenzyme-q8.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

C/C(C)=C\CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC(C(C(OC)=C1OC)=O)=C(C)C1=O

Molecular Formula

C49H74O4

Molecular Weight

727.11

References & Citations

[1]Laura Tempelhagen, et al. Cultivation at high osmotic pressure confers ubiquinone 8-independent protection of respiration on Escherichia coli. J Biol Chem. 2020 Jan 24;295 (4) :981-993. |[2]Block LH, et al. Nonspecific resistance to bacterial infections. Enhancement by ubiquinone-8. J Exp Med. 1978 Nov 1;148 (5) :1228-40.