Recombinant Human Interleukin-2/IL-2 Protein (active)
Product Specifications
Background
Interleukin-2 (IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system; belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes.
Abbreviation
Interleukin-2/IL-2
Synonyms
Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin
UniProt
P60568-1
Accession Number
P60568-1
Expression System
HEK293 cells
Tag
None
Sequence
Ala 21-Thr 153
Field of Research
Immunology
Endotoxin
≤0.01 EU per μg by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Human IL-2 Protein, Tag Free stimulates proliferation of CTLL-2 cells. The specific activity of Human IL-2 Protein, Tag Free is > 0.60 x 10^7 IU/mg, which is calibrated against human IL-2 WHO International Standard.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
15.4 kDa
Observed Molecular Weight
14-22 kDa
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Species
Human
Available Sizes
Documents
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