Anisatin

Product Specifications

UNSPSC Description

Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC50 of ~1.10?μM[1].

Target Antigen

GABA Receptor

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/anisatin.html

Purity

99.0

Smiles

O[C@]12[C@]3([C@@H](C[C@H]2O)C)C[C@@H](OC([C@@H]3O)=O)[C@](O)([C@]14C(OC4)=O)C

Molecular Weight

328.31

References & Citations

[1]Ikeda T, et al. Anisatin modulation of the gamma-aminobutyric acid receptor-channel in rat dorsal root ganglion neurons. Br J Pharmacol. 1999;127(7):1567-1576.|[2]Bao X, et al. Bioavailability and Pharmacokinetics of Anisatin in Mouse Blood by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry. Biomed Res Int. 2020;2020:8835447. Published 2020 Dec 23.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N9506/Anisatin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N9506/Anisatin-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

5230-87-5

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

HY-40354S 1 mg

Tofacitinib-13C3

Ask

View Details

NBP2-12048V 0.1 mL

Mouse Monoclonal B7-H3/CD276 Antibody (MM0104-20J12) [DyLight 405]

Ask