UK-371804
UK-371804 is a urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM.
Product Specifications
CAS Number
[256477-09-5]
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
PAI-1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/UK-371804.html
Purity
98.0
Solubility
DMSO : 8.33 mg/mL (ultrasonic)
Smiles
CC(C(O)=O)(C)NS(=O)(C1=CC2=C(C=C1)C(Cl)=CN=C2NC(N)=N)=O
Molecular Formula
C14H16ClN5O4S
Molecular Weight
385.83
Precautions
H302, H312, H332
References & Citations
[1]Fish PV, et al. Selective urokinase-type plasminogen activator inhibitors. 4. 1- (7-sulfonamidoisoquinolinyl) guanidines. J Med Chem. 2007 May 17;50 (10) :2341-51.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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