Canine DNAM-1 / CD226 Protein, His Tag (SPR verified)
Canine DNAM-1, His Tag (DN1-C52H4) is expressed from human 293 cells (HEK293) . It contains AA Glu 32 - Gln 263 (Accession # E2R115-1) .
Product Specifications
Background
DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.2 kDa. The protein migrates as 36-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
E2R115-1
Expression Region
Glu 32 - Gln 263
Host
HEK293
Target
DNAM-1
Conjugation
Unconjugated
Tag
C-10xHis
Source
Canine
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
28.2 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/DN1-C52H4.pdf
Species
Canine
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