Human CD83 Protein

<strong>Human CD83 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011891_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 250 µg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> HB-15 protein, HB15 protein, CD-83 protein, CD 83 protein, BL-11 protein, CD83, CD83 antigen isoform b precursor protein, BL 11 protein, CD-83, BL11 protein, HB 15 protein, CD 83_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Grosche L, Knippertz I, König C, Royzman D, Wild AB, Zinser E, Sticht H, Muller YA, Steinkasserer A, Lechmann M. The CD83 Molecule - An Important Immune Checkpoint Front Immunol. 2020 Apr 17;11:721._x000D_ 2: Shrestha B, Walton K, Reff J, Sagatys EM, Tu N, Boucher J, Li G, Ghafoor T, Felices M, Miller JS, Pidala J, Blazar BR, Anasetti C, Betts BC, Davila ML. Human CD83-targeted chimeric antigen receptor T cells prevent and treat graft-versus-host disease J Clin Invest. 2020 Sep 1;130(9):4652-4662._x000D_ 3: Ju X, Silveira PA, Hsu WH, Elgundi Z, Alingcastre R, Verma ND, Fromm PD, Hsu JL, Bryant C, Li Z, Kupresanin F, Lo TH, Clarke C, Lee K, McGuire H, Fazekas de St Groth B, Larsen SR, Gibson J, Bradstock KF, Clark GJ, Hart DN. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population J Immunol. 2016 Dec 15;197(12):4613-4625._x000D_ 4: Wong KY, Baron R, Seldon TA, Jones ML, Rice AM, Munster DJ. CD83 Antibody Inhibits Human B Cell Responses to Antigen as well as Dendritic Cell-Mediated CD4 T Cell Responses J Immunol. 2018 May 15;200(10):3383-3396._x000D_ 5: Stein MF, Blume K, Heilingloh CS, Kummer M, Biesinger B, Sticht H, Steinkasserer A. CD83 and GRASP55 interact in human dendritic cells Biochem Biophys Res Commun. 2015 Mar 27;459(1):42-8._x000D_ 6: Zinser E, Naumann R, Wild AB, Michalski J, Deinzer A, Stich L, Kuhnt C, Steinkasserer A, Knippertz I. Endogenous Expression of the Human CD83 Attenuates EAE Symptoms in Humanized Transgenic Mice and Increases the Activity of Regulatory T Cells Front Immunol. 2019 Jun 25;10:1442._x000D_ 7: Huo S, Zhang J, Wu F, Zuo Y, Cui D, Li X, Zhong Z, Zhong F. Porcine CD83 is a glycosylated dimeric protein existing naturally in membrane-bound and soluble forms Dev Comp Immunol. 2019 Jan;90:60-69._x000D_ 8: Ma N, Li X, Jiang H, Dai Y, Xu G, Zhang Z. Influenza Virus Neuraminidase Engages CD83 and Promotes Pulmonary Injury J Virol. 2021 Jan 13;95(3):e01753-20._x000D_ 9: Zhang L, Narayanan N, Brand SR, Nicolette CA, Baroja M, Arp J, Wang H, Moo-Young M, Chou CP. Structural identification of recombinant human CD83 mutant variant as a potent therapeutic protein Protein Expr Purif. 2010 Oct;73(2):140-6._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15746244">10: Klein E, Koch S, Borm B, Neumann J, Herzog V, Koch N, Bieber T. CD83 localization in a recycling compartment of immature human monocyte-derived dendritic cells Int Immunol. 2005 Apr;17(4):477-87. </a>_x000D_ _x000D_ <strong>Products Related to Human CD83 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>