Cholesterol oxidase, rhodococcus sp
Product Specifications
UNSPSC Description
Cholesterol oxidase, Rhodococcus sp. is a key enzyme in the cholesterol degradation process. It catalyzes the isomerization and oxidation of cholesterol mediated by the coenzyme FAD. Research indicates that cholesterol oxidase plays a crucial role in the pathogenicity of Mycobacterium tuberculosis by modulating the host macrophage immune response through inhibition of the Toll-like receptor 2 (TLR2) signaling pathway, thereby enhancing the survival of Mycobacterium tuberculosis. Cholesterol oxidase, from Rhodococcus sp., shows potential for research in the field of tuberculosis[1][2].
Target Antigen
Toll-like Receptor (TLR)
Type
Enzyme
Related Pathways
Immunology/Inflammation
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cholesterol-oxidase-rhodococcus-sp.html
Smiles
[Cholesterol oxidase, rhodococcus sp]
References & Citations
[1]Cui H, et al. Heterologous Expression and Function of Cholesterol Oxidase: A Review. Protein Pept Lett. 2023;30(7):531-540.|[2]Brzostek A, et al. Cholesterol oxidase is required for virulence of Mycobacterium tuberculosis. FEMS Microbiol Lett. 2007 Oct;275(1):106-12.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2848A/Cholesterol-oxidase-rhodococcus-sp-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2848A/
Clinical Information
No Development Reported
CAS Number
9028-76-6
Available Sizes
Curated Selection
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