Penduletin
Penduletin is a flavone, that can be isolated from Brickelia pendula and Vitex negundo. Penduletin shows anticancer activity. Penduletin induces apoptosis in the cancer cells through ROS generation[1][2].
Product Specifications
CAS Number
569-80-2
UNSPSC
12352005
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/penduletin.html
Purity
99.59
Solubility
Ethanol : 5 mg/mL (ultrasonic; warming)
Smiles
O=C1C2=C(O)C(OC)=C(OC)C=C2OC(C3=CC=C(O)C=C3)=C1OC
Molecular Formula
C18H16O7
Molecular Weight
344.32
References & Citations
[1]Flores S E, et al.The structure of pendulin and penduletin: a new flavonol glucoside isolated from brickelia pendula[J].Tetrahedron, 1958, 2 (3-4) :308-315.|[2]Vo GV, et al. In silico and in vitro studies on the anti-cancer activity of artemetin, vitexicarpin and penduletin compounds from Vitex negundo. Saudi Pharm J. 2022 Sep;30 (9) :1301-1314.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LS051246-100ug 100 µg
SHISA5 (NM_016479) Human Over-expression Lysate
Sign In for Pricing
View Details 
C2258-94J-ML490 100 µL
CD8a (Ly2, T cell Co-receptor, Leu2, T8) (MaxLight 490) discontinued
Sign In for Pricing
View Details 
MBS1084820-01 0.02 mg (E-Coli)
Recombinant Salmonella paratyphi A Molybdenum cofactor biosynthesis protein A (moaA)
Sign In for Pricing
View Details MBS1084820-02 0.02 mg (Yeast)
Recombinant Salmonella paratyphi A Molybdenum cofactor biosynthesis protein A (moaA)
Sign In for Pricing
View Details