Penduletin
Penduletin is a flavone, that can be isolated from Brickelia pendula and Vitex negundo. Penduletin shows anticancer activity. Penduletin induces apoptosis in the cancer cells through ROS generation[1][2].
Product Specifications
CAS Number
[569-80-2]
UNSPSC
12352005
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/penduletin.html
Purity
99.59
Solubility
Ethanol : 5 mg/mL (ultrasonic; warming)
Smiles
O=C1C2=C(O)C(OC)=C(OC)C=C2OC(C3=CC=C(O)C=C3)=C1OC
Molecular Formula
C18H16O7
Molecular Weight
344.32
References & Citations
[1]Flores S E, et al.The structure of pendulin and penduletin: a new flavonol glucoside isolated from brickelia pendula[J].Tetrahedron, 1958, 2 (3-4) :308-315.|[2]Vo GV, et al. In silico and in vitro studies on the anti-cancer activity of artemetin, vitexicarpin and penduletin compounds from Vitex negundo. Saudi Pharm J. 2022 Sep;30 (9) :1301-1314.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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