Curculigoside

Curculigoside is the main saponin in C. orchioide, exerts significant antioxidant, anti-osteoporosis, antidepressant and neuroprotection effects. Curculigoside possesses significant anti-arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF-κB signaling pathway[1].

Product Specifications

CAS Number

[85643-19-2]

UNSPSC

12352005

Target

JAK; NF-κB; STAT

Type

Natural Products

Related Pathways

Epigenetics; JAK/STAT Signaling; NF-κB; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/curculigoside.html

Concentration

10mM

Purity

99.82

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 2 mg/mL

Smiles

O=C(C(C(OC)=CC=C1)=C1OC)OCC(C=C(O)C=C2)=C2O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO

Molecular Formula

C22H26O11

Molecular Weight

466.44

References & Citations

[1]Tan S, et al. Curculigoside exerts significant anti arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF κB signaling pathway. Mol Med Rep. 2019 Mar;19 (3) :2057-2064.