AF/LE Purified Anti-Mouse/Human GAL3 Antibody[M3/38]

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.

MAC; Galactose-specific lectin; Galactoside-Binding Soluble; Galectin; Lectin L; GAL; CBP; LGALS3; CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2; Galactoside-Binding Soluble 3; Lectin; Galectin-3; Gal-3; L-31;35 kDa lectin; CBP 35; Galactose-specific lectin 3; IgE-binding protein; Laminin-binding protein; Lectin L-29; Mac-2 antigen; Carbohydrate binding protein 35; Carbohydrate-binding protein 35; galactose binding; galactoside binding soluble 3; Galactoside-binding protein; galectin 3; Galectin 3 internal gene; Galectin3; GBP; IgE binding protein; included; L 31; L 34; L-34 galactoside-binding lectin; Lectin; Galactoside-Binding Soluble 3; LEG3; MAC 2 antigen; Mac-2; Macrophage galactose-specific lectin; MGC105387; P35; soluble 3

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.