USP7-IN-3
USP7-IN-3 (Compound 5) is an effective and selective allosteric inhibitor of ubiquitin-specific protease 7 (USP7) . USP7-IN-3 can be used for research on acute lymphoblastic leukemia[1].
Product Specifications
CAS Number
2202738-42-7
UNSPSC
12352005
Target
Deubiquitinase; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/USP7-IN-3.html
Purity
99.06
Solubility
DMSO : 90 mg/mL (ultrasonic)
Smiles
O=C(N1CCC(CN2C(C3=NN(C)C(C4=CC=C(CN)C=C4)=C3N=C2)=O)(O)CC1)C[C@@H](C(F)(F)F)C5=CC=CC=C5
Molecular Formula
C29H31F3N6O3
Molecular Weight
568.59
References & Citations
[1]Gavory G, et al. Discovery and characterization of highly potent and selective allosteric USP7 inhibitors. Nat Chem Biol. 2018 Feb;14 (2) :118-125.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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