SIRT2-IN-8
SIRT2-IN-8 is a potent SIRT2 inhibitor. SIRT2-IN-8 can be used for Huntington’s and Parkinson’s diseases research[1].
Product Specifications
CAS Number
[115687-05-3]
UNSPSC
12352005
Hazard Statement
H301, H315, H319, H335
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sirt2-in-8.html
Purity
99.32
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=C(Cl)C=C1)N(CC2)CCN2C(C=C3)=C(C=CC=N4)C4=C3[N+]([O-])=O
Molecular Formula
C20H17ClN4O3
Molecular Weight
396.83
Precautions
H301, H315, H319, H335
References & Citations
[1]Bodner RA, Outeiro TF, Altmann S, et al. Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases. Proc Natl Acad Sci U S A. 2006;103 (11) :4246-4251.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT2
Available Sizes
Curated Selection
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