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Myo-Inositol trispyrophosphate (hexa-triethylamine)

Selected Variant

HY-141510A-01

Size: 5 mg

Myo-Inositol trispyrophosphate (ITPP) hexa-triethylamine is a salt form of inositol triphosphate (ITPP) . myo-Inositol trispyrophosphate hexa-triethylamine is a membrane-permeant hemoglobin allosteric regulator. myo-Inositol trispyrophosphate hexa-triethylamine enhances the oxygen release capacity of red blood cells by reducing the affinity of hemoglobin to oxygen. myo-Inositol trispyrophosphate hexa-triethylamine can be used in the study of cardiovascular disease and cancer[1][2][3].

Product Specifications

CAS Number

851086-77-6

Product Name Alternative

ITPP (hexa-triethylamine)

UNSPSC

12352128

Target

HIF/HIF Prolyl-Hydroxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/myo-inositol-trispyrophosphate-hexa-triethylamine.html

Purity

98.0

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

O=P1(O[C@]2([H])[C@@]3([H])[C@@](OP(O)(OP(O)(O3)=O)=O)([H])[C@]4([H])[C@@](OP(O)(OP(O)(O4)=O)=O)([H])[C@@]2([H])OP(O)(O1)=O)O.CCN(CC)CC.[6]

Molecular Formula

C6H12O21P6.6C6H15N

Molecular Weight

1213.13

References & Citations

[1]Fylaktakidou KC, et al. Inositol tripyrophosphate: a new membrane permeant allosteric effector of haemoglobin. Bioorg Med Chem Lett. 2005 Mar 15;15 (6) :1605-8. |[2]Oknińska M, et al. Treatment of hypoxia-dependent cardiovascular diseases by myo-inositol trispyrophosphate (ITPP) -enhancement of oxygen delivery by red blood cells. J Cell Mol Med. 2020 Feb;24 (3) :2272-2283.|[3]Raykov Z, et al. Myo-inositol trispyrophosphate-mediated hypoxia reversion controls pancreatic cancer in rodents and enhances gemcitabine efficacy. Int J Cancer. 2014 Jun 1;134 (11) :2572-82.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Price

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