KF-14124
KF-14124, an orally active organic nitrate, a long-acting vasodilator with highly selective venous dilating action. KF-14124 is used in the study for angina pectoris. KF-14124 shows good oral inhibition of lysine-vasopressin induced coronary vasospasm with a potency[1][2].
Product Specifications
CAS Number
134186-26-8
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/kf-14124.html
Smiles
O=[N+]([O-])O[C@@H]1[C@](OC[C@@H]2N3CCN(CCCSC4=CC=CC=C4)CC3)([H])[C@]2([H])OC1
Molecular Formula
C19H27N3O5S
Molecular Weight
409.50
References & Citations
[1]1,4:3,6-Dianhydrohexitol nitrate derivatives. I. Synthesis and antianginal activity of alkylpiperazine derivatives. Chem Pharm Bull (Tokyo) . 1993 Jun;41 (6) :1091-9.|[2]Giorgio Bertolini, et al. Overview: Recent Advances in Organic Nitrates. Current Opinion on Therapeutic Patents Volume 3, 1993 - Issue 10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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