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Biotinoyl tripeptide-1

Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases[1][2].

Product Specifications

CAS Number

[299157-54-3]

Product Name Alternative

Biotinyl-GHK; Bio-GHK

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Amyloid-β; Reactive Oxygen Species (ROS)

Type

Peptides

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/biotinoyl-tripeptide-1.html

Concentration

10mM

Purity

99.02

Solubility

DMSO : 87.5 mg/mL (ultrasonic)

Smiles

NCCCC[C@H](NC([C@@H](NC(CNC(CCCC[C@@H]1SC[C@]([H])(N2)[C@@]1(NC2=O)[H])=O)=O)CC3=CNC=N3)=O)C(O)=O

Molecular Formula

C24H38N8O6S

Molecular Weight

566.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang L, et al. Overview of Peptides and Their Potential Roles in Skin Health and Beauty. J Pept Sci. 2025 Feb;31 (2) :e3668.|[2]Tosto R, et al. New Biotinylated GHK and Related Copper (II) Complex: Antioxidant and Antiglycant Properties In Vitro against Neurodegenerative Disorders. Molecules. 2023 Sep 20;28 (18) :6724.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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