Human CAPS Protein

<strong>Human CAPS Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011686_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Calcyphosin, CAPS1 protein, Calcyphosine protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Coll RC, Robertson AA, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, Vetter I, Dungan LS, Monks BG, Stutz A, Croker DE, Butler MS, Haneklaus M, Sutton CE, Núñez G, Latz E, Kastner DL, Mills KH, Masters SL, Schroder K, Cooper MA, O'Neill LA. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases Nat Med. 2015 Mar;21(3):248-55._x000D_ 2: Booshehri LM, Hoffman HM. CAPS and NLRP3 J Clin Immunol. 2019 Apr;39(3):277-286._x000D_ 3: Lachmann HJ. Periodic fever syndromes Best Pract Res Clin Rheumatol. 2017 Aug;31(4):596-609._x000D_ 4: Kuemmerle-Deschner JB, Ozen S, Tyrrell PN, Kone-Paut I, Goldbach-Mansky R, Lachmann H, Blank N, Hoffman HM, Weissbarth-Riedel E, Hugle B, Kallinich T, Gattorno M, Gul A, Ter Haar N, Oswald M, Dedeoglu F, Cantarini L, Benseler SM. Diagnostic criteria for cryopyrin-associated periodic syndrome (CAPS) Ann Rheum Dis. 2017 Jun;76(6):942-947._x000D_ 5: Youm YH, Nguyen KY, Grant RW, Goldberg EL, Bodogai M, Kim D, D'Agostino D, Planavsky N, Lupfer C, Kanneganti TD, Kang S, Horvath TL, Fahmy TM, Crawford PA, Biragyn A, Alnemri E, Dixit VD. The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease Nat Med. 2015 Mar;21(3):263-9._x000D_ 6: Georgin-Lavialle S, Ducharme-Benard S, Sarrabay G, Savey L, Grateau G, Hentgen V. Systemic autoinflammatory diseases: Clinical state of the art Best Pract Res Clin Rheumatol. 2020 Aug;34(4):101529._x000D_ 7: Kacar M, Pathak S, Savic S. Hereditary systemic autoinflammatory diseases and Schnitzler's syndrome Rheumatology (Oxford). 2019 Nov 1;58(Suppl 6):vi31-vi43._x000D_ 8: Marzano AV, Damiani G, Genovese G, Gattorno M. A dermatologic perspective on autoinflammatory diseases Clin Exp Rheumatol. 2018 Jan-Feb;36 Suppl 110(1):32-38. Epub 2018 May 3._x000D_ 9: He Y, Zeng MY, Yang D, Motro B, Núñez G. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux Nature. 2016 Feb 18;530(7590):354-7._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25586657">10: Marzano AV, Tavecchio S, Venturini M, Sala R, Calzavara-Pinton P, Gattorno M. Urticarial vasculitis and urticarial autoinflammatory syndromes G Ital Dermatol Venereol. 2015 Feb;150(1):41-50. Epub 2015 Jan 14.</a>_x000D_ _x000D_ <strong>Products Related to Human CAPS Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>