LMPTP-A Protein

<strong>LMPTP-A Protein</strong>_x000D_ <strong>Catalog number:</strong> B2019318_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5  µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 44.5 kDa_x000D_ <strong>Supplied as:</strong> Resin_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −70°C_x000D_ <strong>Keywords:</strong> LMPTP-A Protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Tailor P, Gilman J, Williams S, Mustelin T. A novel isoform of the low molecular weight phosphotyrosine phosphatase, LMPTP-C, arising from alternative mRNA splicing Eur J Biochem. 1999 Jun;262(2):277-82._x000D_ 2: Bottini N, Stefanini L, Williams S, Alonso A, Jascur T, Abraham RT, Couture C, Mustelin T. Activation of ZAP-70 through specific dephosphorylation at the inhibitory Tyr-292 by the low molecular weight phosphotyrosine phosphatase (LMPTP) J Biol Chem. 2002 Jul 5;277(27):24220-4._x000D_ 3: Ardecky RJ, Hedrick MP, Stanford SM, Bliss MR, Zou J, Gosalia P, Yamamoto F, Milewski M, Barron N, Sun Q, Ganji S, Mehta A, Sugarman E, Nguyen K, Vasile S, Suyama E, Mangravita-Novo A, Salaniwal S, Kung P, Smith LH, Sergienko E, Chung TDY, Pinkerton AB, Bottini N. Allosteric Small Molecule Inhibitors of LMPTP 2014 Apr 15 [updated 2015 Jan 16]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–._x000D_ 4: Stanford SM, Nguyen TP, Chang J, Zhao Z, Hackman GL, Santelli E, Sanders CM, Katiki M, Dondossola E, Brauer BL, Diaz MA, Zhan Y, Ramsey SH, Watson PA, Sankaran B, Paindelli C, Parietti V, Mikos AG, Lodi A, Bagrodia A, Elliott A, McKay RR, Murali R, Tiziani S, Kettenbach AN, Bottini N. Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy Sci Adv. 2024 Feb 2;10(5):eadg7887._x000D_ 5: Stanford SM, Collins M, Diaz MA, Holmes ZJ, Gries P, Bliss MR, Lodi A, Zhang V, Tiziani S, Bottini N. The low molecular weight protein tyrosine phosphatase promotes adipogenesis and subcutaneous adipocyte hypertrophy J Cell Physiol. 2021 Sep;236(9):6630-6642._x000D_ 6: Stanford SM, Aleshin AE, Zhang V, Ardecky RJ, Hedrick MP, Zou J, Ganji SR, Bliss MR, Yamamoto F, Bobkov AA, Kiselar J, Liu Y, Cadwell GW, Khare S, Yu J, Barquilla A, Chung TDY, Mustelin T, Schenk S, Bankston LA, Liddington RC, Pinkerton AB, Bottini N. Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase Nat Chem Biol. 2017 Jun;13(6):624-632._x000D_ 7: Morris A. Diabetes: LMPTP inhibitors - potential treatment for type 2 diabetes? Nat Rev Endocrinol. 2017 Jun;13(6):316._x000D_ 8: Alicka M, Kornicka-Garbowska K, Roecken M, Marycz K. Inhibition of the Low Molecular Weight Protein Tyrosine Phosphatase (LMPTP) as a Potential Therapeutic Strategy for Hepatic Progenitor Cells Lipotoxicity-Short Communication Int J Mol Sci. 2019 Nov 22;20(23):5873._x000D_ 9: Bourebaba L, Łyczko J, Alicka M, Bourebaba N, Szumny A, Fal AM, Marycz K. Inhibition of Protein-tyrosine Phosphatase PTP1B and LMPTP Promotes Palmitate/Oleate-challenged HepG2 Cell Survival by Reducing Lipoapoptosis, Improving Mitochondrial Dynamics and Mitigating Oxidative and Endoplasmic Reticulum Stress J Clin Med. 2020 May 1;9(5):1294._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/10336608">10: Tailor P, Gilman J, Williams S, Mustelin T. A novel isoform of the low molecular weight phosphotyrosine phosphatase, LMPTP-C, arising from alternative mRNA splicing Eur J Biochem. 1999 Jun;262(2):277-82. </a>_x000D_ _x000D_ <strong>Products Related to LMPTP-A Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>