PFKFB3-IN-2
PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. PFKFB3-IN-2 has potential applications in cancer, neurodegenerative diseases, autoimmune diseases, inflammatory diseases, multiple sclerosis, metabolic diseases, angiogenesis inhibition and other diseases[1].
Product Specifications
CAS Number
[794552-84-4]
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pfkfb3-in-2.html
Purity
99.86
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC(S(=O)(NC2=CC=C(C(O)=C2)C(O)=O)=O)=C1)O
Molecular Formula
C14H11NO7S
Molecular Weight
337.30
References & Citations
[1]Fedichev P, et al. Pfkfb3 inhibitors and their uses. World Intellectual Property Organization. WO2020080979.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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