Dyrk1A-IN-10
Dyrk1A-IN-10 (compound B4) is a DYRK1A inhibitor with antidiabetic activity. Dyrk1A-IN-10 can promote pancreatic β-cell proliferation, increase insulin secretion, and lower blood sugar[1].
Product Specifications
CAS Number
2891824-14-7
UNSPSC
12352005
Target
DYRK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dyrk1a-in-10.html
Smiles
O=C(N(C1C)CCC2=C1NC3=C2C=C(OC)C=C3)/C=C/C4=CC=C(Cl)C=C4
Molecular Formula
C22H21ClN2O2
Molecular Weight
380.87
References & Citations
[1]Li Guan, et al. "Design, synthesis, and biological evaluation of β-carboline-cinnamic acid derivatives as DYRK1A inhibitors in the treatment of diabetes." Bioorganic Chemistry (2024) : 107676.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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