IZ-Chol
Product Specifications
UNSPSC Description
IZ-Chol (IZ-Cholesterol) is an ionizable cationic lipid containing cholesterol. IZ-Chol-LNPs is highly potential to effectively complex with DNA, and endosome escape mechanisms mediated by proton sponge effect[1].
Target Antigen
Liposome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/iz-chol.html
Smiles
C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCCN4C=CN=C4)=O)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCCC(C)C)C
Molecular Weight
537.82
References & Citations
[1]Yajing Wang, et al. Design, synthesis, and in vitro gene transfer efficacy of novel ionizable cholesterol derivatives. J Liposome Res. 2024 Apr 2:1-13.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159859/IZ-Chol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159859/
Clinical Information
No Development Reported
CAS Number
191990-35-9
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