ARP
ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 104 nucleotides) [1].
Product Specifications
CAS Number
[139585-03-8]
Product Name Alternative
Aldehyde reactive probe
UNSPSC
12352200
Target
Fluorescent Dye
Type
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/arp.html
Solubility
10 mM in DMSO
Smiles
NOCC(NNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O
Molecular Formula
C12H21N5O4S
Molecular Weight
331.39
References & Citations
[1]Kubo K, et al., A novel, sensitive, and specific assay for abasic sites, the most commonly produced DNA lesion. Biochemistry. 1992 Apr 14;31 (14) :3703-8.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Curated Selection
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