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ARP

Product Specifications

UNSPSC Description

ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 104 nucleotides)[1].

Target Antigen

Fluorescent Dye

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/arp.html

Solubility

10 mM in DMSO

Smiles

NOCC(NNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O

Molecular Weight

331.39

References & Citations

[1]Kubo K, et al., A novel, sensitive, and specific assay for abasic sites, the most commonly produced DNA lesion. Biochemistry. 1992 Apr 14;31(14):3703-8.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-157916/ARP-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-157916/

Clinical Information

No Development Reported

CAS Number

139585-03-8

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