RB-CO-PEG5-C2-CO-VH032
RB-CO-PEG5-C2-CO-VH032 is a TRIM24 degrader that can inactivat the mTOR signaling pathway[1].
Product Specifications
UNSPSC
12352005
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rb-co-peg5-c2-co-vh032.html
Smiles
O[C@@H](C)[C@H](NC([C@H](CCCNC(N)=N)NC([C@H]1N(C([C@@H](NC(CCOCCOCCOCCOCCOCCC(N[C@H](C(N2C[C@H](O)C[C@H]2C(NCC3=CC=C(C4=C(C)N=CS4)C=C3)=O)=O)C(C)(C)C)=O)=O)CO)=O)CCC1)=O)=O)C(O)=O
Molecular Formula
C54H85N11O17S
Molecular Weight
1192.38
References & Citations
[1]Da Ren, et al. Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer. Cell Death Differ. 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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