Clotrimazole-d10
Clotrimazole-d10 is deuterated labeled Clotrimazole. Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.
Product Specifications
UNSPSC
12352005
Target
Antibiotic; Autophagy; Bacterial; Fungal; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Autophagy; Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Purity
97.51
Solubility
10 mM in DMSO
Smiles
ClC1=CC=CC=C1C(N2C=CN=C2)(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H]
Molecular Formula
C22H7D10ClN2
Molecular Weight
354.90
References & Citations
[1]Schaller K. In vitro antibacterial activity of different clotrimazole formulations. Chemotherapy. 1982;28 Suppl 1:32-6.|[2]Sawyer PR, Clotrimazole: a review of its antifungal activity and therapeutic efficacy. Drugs. 1975;9 (6) :424-47.|[3]Witzke A, Inhibition of the gastric H, K-ATPase by clotrimazole. Biochemistry. 2010 Jun 1;49 (21) :4524-32.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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