N-Boc-N-bis (PEG2-propargyl)

N-Boc-N-bis (PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Boc-N-bis (PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[2100306-86-1]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-boc-n-bis-peg2-propargyl.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)N(CCOCCOCC#C)CCOCCOCC#C

Molecular Formula

C19H31NO6

Molecular Weight

369.45

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562