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Collagen V α2 (Cleaved-Leu1229) rabbit pAb

This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq, Jul 2008]

UniProt

P05997

Swiss Prot

P05997

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human Collagen V α2 (Cleaved-Leu1229)

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight

145kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

145kD

Fragment

IgG

Subcellular Location

Secreted, extracellular space, extracellular matrix .

Other Product Names

Collagen alpha-2 (V) chain

Gene ID (Human)

1290

Available Sizes

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