E-Cadherin Recombinant Mouse Monoclonal Antibody [A0-G11-2-R]
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Cadherin-1 CAM 120/80 Epithelial cadherin (E-cadherin) Uvomorulin
Abbreviation
CDH1
Swiss Prot
P12830 Human, P09803 Mouse, Q9R0T4 Rat
Cellular Locus
Cell membrane, Endosome, Golgi apparatus.
Host
Mouse
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within mouse E-Cadherin aa 350-550.
Isotype
IgG
Clone
A0-G11-2-R
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB, IHC, mIHC
Positive Control
Concentration
1mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC: 1:200-1:10,000 ;mIHC: 1:4,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 98 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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