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Extracellular death factor

Extracellular death factor (EDF) is the only single signaling molecule involved in Escherichia coli quorum sensing, and can initiate MAZEF-mediated cell death. Extracellular death factor significantly amplifies the endoribonucleolytic activities of both MazF and ChpBK[1].

Product Specifications

CAS Number

[960129-66-2]

Product Name Alternative

EDF

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/extracellular-death-factor.html

Purity

98.01

Solubility

10 mM in DMSO

Smiles

O=C(N)C[C@@H](C(O)=O)NC([C@H](CC(N)=O)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)N)=O)=O)=O)=O

Molecular Formula

C27H36N10O10

Molecular Weight

660.64

References & Citations

[1]Belitsky M, et al. The Escherichia coli extracellular death factor EDF induces the endoribonucleolytic activities of the toxins MazF and ChpBK. Mol Cell. 2011;41 (6) :625-635.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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