Extracellular death factor
Extracellular death factor (EDF) is the only single signaling molecule involved in Escherichia coli quorum sensing, and can initiate MAZEF-mediated cell death. Extracellular death factor significantly amplifies the endoribonucleolytic activities of both MazF and ChpBK[1].
Product Specifications
CAS Number
960129-66-2
Product Name Alternative
EDF
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/extracellular-death-factor.html
Purity
98.01
Solubility
10 mM in DMSO
Smiles
O=C(N)C[C@@H](C(O)=O)NC([C@H](CC(N)=O)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)N)=O)=O)=O)=O
Molecular Formula
C27H36N10O10
Molecular Weight
660.64
References & Citations
[1]Belitsky M, et al. The Escherichia coli extracellular death factor EDF induces the endoribonucleolytic activities of the toxins MazF and ChpBK. Mol Cell. 2011;41 (6) :625-635.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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