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USP30 inhibitor 11

USP30 inhibitor 11 is a selective and potent ubiquitin specific peptidase 30 (USP30) inhibitor with an IC50 of 0.01 μΜ, the example 83 extracted from patent WO2017009650A1. USP30 inhibitor 11 is used for the study of cancer and conditions involving mitochondrial dysfunction[1].

Product Specifications

CAS Number

[2067332-64-1]

UNSPSC

12352005

Target

Deubiquitinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/usp30-inhibitor-11.html

Purity

99.81

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

O=C([C@H]1N(C#N)CCC1)N(C2=NC(C3=NC(C#N)=C(OC)C=C3)=CS2)C

Molecular Formula

C17H16N6O2S

Molecular Weight

368.41

References & Citations

[1]Mark Kemp, et al. Cyanopyrrolidines as dub inhibitors for the treatment of cancer. Patent WO 2017009650 A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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