USP30 inhibitor 11
USP30 inhibitor 11 is a selective and potent ubiquitin specific peptidase 30 (USP30) inhibitor with an IC50 of 0.01 μΜ, the example 83 extracted from patent WO2017009650A1. USP30 inhibitor 11 is used for the study of cancer and conditions involving mitochondrial dysfunction[1].
Product Specifications
CAS Number
[2067332-64-1]
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp30-inhibitor-11.html
Purity
99.81
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(C#N)CCC1)N(C2=NC(C3=NC(C#N)=C(OC)C=C3)=CS2)C
Molecular Formula
C17H16N6O2S
Molecular Weight
368.41
References & Citations
[1]Mark Kemp, et al. Cyanopyrrolidines as dub inhibitors for the treatment of cancer. Patent WO 2017009650 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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