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ART26.12

Product Specifications

CAS Number

2766800-24-0

UNSPSC Description

ART26.12 is an orally active FABP5 inhibitor with anti-cannabinoid properties. ART26.12 effectively prevents and alleviates Oxaliplatin (HY-17371)-induced pain through lipid modulation and cannabinoid receptor activation[1].

Target Antigen

Cannabinoid Receptor; FABP

Type

Reference compound

Related Pathways

GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/art26-12.html

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C([C@H]1[C@H](C2=C(C=CC=C2)OC)[C@@H]([C@H]1C3=C(C=CC=C3)OC)C(O)=O)OC4CC5=CC=CC=C5C4

Molecular Weight

472.53

References & Citations

[1]Warren G, et al. Discovery and Preclinical Evaluation of a Novel Inhibitor of FABP5, ART26.12, Effective in Oxaliplatin-Induced Peripheral Neuropathy. J Pain. 2024 Jul;25(7):104470.

Shipping Conditions

Room Temperature

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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