ART26.12
Product Specifications
CAS Number
2766800-24-0
UNSPSC Description
ART26.12 is an orally active FABP5 inhibitor with anti-cannabinoid properties. ART26.12 effectively prevents and alleviates Oxaliplatin (HY-17371)-induced pain through lipid modulation and cannabinoid receptor activation[1].
Target Antigen
Cannabinoid Receptor; FABP
Type
Reference compound
Related Pathways
GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/art26-12.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C([C@H]1[C@H](C2=C(C=CC=C2)OC)[C@@H]([C@H]1C3=C(C=CC=C3)OC)C(O)=O)OC4CC5=CC=CC=C5C4
Molecular Weight
472.53
References & Citations
[1]Warren G, et al. Discovery and Preclinical Evaluation of a Novel Inhibitor of FABP5, ART26.12, Effective in Oxaliplatin-Induced Peripheral Neuropathy. J Pain. 2024 Jul;25(7):104470.
Shipping Conditions
Room Temperature
Clinical Information
No Development Reported
Available Sizes
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