5-Hydroxyferulic acid

5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate[1][2][3].

Product Specifications

CAS Number

[1782-55-4]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

COMT; Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-hydroxyferulic-acid.html

Concentration

10mM

Purity

99.42

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)/C=C/C1=CC(OC)=C(O)C(O)=C1

Molecular Formula

C10H10O5

Molecular Weight

210.18

Precautions

H315, H319, H335

References & Citations

[1]K Parvathi, et al. Substrate Preferences of O-methyltransferases in Alfalfa Suggest New Pathways for 3-O-methylation of Monolignols. Plant J. 2001 Jan;25 (2) :193-202.|[2]S Maury, et al. Tobacco O-methyltransferases Involved in Phenylpropanoid Metabolism. The Different Caffeoyl-Coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and Caffeic acid/5-hydroxyferulic Acid 3/5-O-methyltransferase Classes Have Distinct Substrate Specificities and Expression Patterns. Plant Physiol. 1999 Sep;121 (1) :215-24.|[3]Inoue, et al. Substrate Preferences of Caffeic acid/5-hydroxyferulic Acid 3/5-O-methyltransferases in Developing Stems of Alfalfa (Medicago Sativa L.) . Arch Biochem Biophys. 2000 Mar 1;375 (1) :175-82.